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Glutaminase C-IN-1

CAS No. 311795-38-7

Glutaminase C-IN-1 ( GLS-IN-968; Glutaminase inhibitor-968 )

Catalog No. M17473 CAS No. 311795-38-7

Glutaminase C-IN-1 is a Glutaminase C allosteric inhibitor.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 50 In Stock
10MG 80 In Stock
25MG 149 In Stock
50MG 258 In Stock
100MG 383 In Stock
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Biological Information

  • Product Name
    Glutaminase C-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    Glutaminase C-IN-1 is a Glutaminase C allosteric inhibitor.
  • Description
    GLS-IN-968 is an allosteric inhibitor of glutaminase (GLS). It acts by blocking Rho-GTPase-dependent transformation of fibroblasts and suppressing breast cancer cell growth and invasive activity in vitro.
  • Synonyms
    GLS-IN-968; Glutaminase inhibitor-968
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Glutaminase C
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    311795-38-7
  • Formula Weight
    475.43
  • Molecular Formula
    C27H27BrN2O
  • Purity
    98%
  • Solubility
    DMSO : 25 mg/mL. 52.59 mM;
  • SMILES
    CC1(CC2=C(C(Nc3c2c2ccccc2cc3)c2cc(c(cc2)N(C)C)Br)C(=O)C1)C
  • Chemical Name
    5-[3-Bromo-4-(dimethylamino)phenyl]-2,3,5,6-tetrahydro-2,2-dimethylbenzo[a]phenanthridin-4(1H)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Stalnecker CA, et al. Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):394-9.
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